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ea0035p1099 | Thyroid Cancer | ECE2014

DNMT1 expression in papillary thyroid carcinoma

Brehar Andreea , Procopiuc Camelia , Paun Diana , Manda Dana , Oros Sabina , Caragheorgheopol Andra , Bulgar Alexandra , Brehar Felix , Dumitrescu Cristina , Gherlan Iuliana , Ghemigian Mircea , Stanescu Bogdan , Brasoveanu Daniel , Terzea Dana , Ioachim Dumitru , Plesa Adriana , Huica Irina , Iancu Iulia , Badiu Corin , Dumitrache Constantin

Introduction: In human cancer cells DNMTs are responsible for both de novo and maintenance methylation of tumor suppressor genes. Many studies have analyzed the relationship between the altered expression of DNMT1 and DNA methylation in cancer.Aim: To analyze DNMT1 expression in thyroid papillary carcinoma.Design: 49 patients aged 10–82 years hospitalized for thyroidectomy were included between January 2013 and July 2...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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